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diagnosis differential rheumatology causes erythematosus sle systemic cardiology endocarditis infectiousdiseases treatment abscess activation algorithm arthritis carcinoma cerebritis cns conditions elevatedmcv
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... (e.g. autoimmune ... ): Lupus, Rheumatoid
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(eg, systemic juvenile ... • Infection (eg ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Demyelinating syndromes ... pain (20%) Renal disease ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia (
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Algorithm Normal Blood ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Cardiac injury (e.g ... Pericardial perforation (e.g ... pericarditis) Uremia ... Mediterranean fever ... Systemic lupus
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 Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... , Vasculitis (e.g ... arteritis • Bloody ... differential #diagnosis #rheumatology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Anemia (common) ... night sweats, fever ... Budd Chiari syndrome ... Recombinant cytokines (e.g ... kinase inhibitors (e.g
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