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diagnosis differential causes rheumatology management arthritis erythematosus nephrology peds signs sle symptoms systemic activation aki algorithm anemia bleeding bruising cerebritis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... disease or drugs e.g ... Post-infectious GN, Lupus ... AIN) • Drugs (e.g
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
• Reactive (e.g ... Enteropathic (e.g ... Sicca) Syndrome ... Rheumatic Fever Acute ... Enteropathic (e.g
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Diagnosis of Lupus ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Causes of Acute ... idiopathic* Acute ... Cardiac injury (e.g ... Pericardial perforation (e.g ... Systemic lupus
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 SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Pleural effusions • Acute
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... Criteria HRS-AKI (Acute ... nephrotoxics (e.g ... HRS-NAKI (Non-Acute ... HRSAKI #HRSNAKI #hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... Diagnosis #Management #Hematology
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