12 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... and CNS • Headache ... vein thrombosis Hematologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus ( ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... #rheumatology #
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
• Reactive (e.g ... Enteropathic (e.g ... Erythematosus ... Sicca) Syndrome ... Enteropathic (e.g
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... disorders (Systemic lupus ... erythematosus,
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... nervous system (CNS ... underlying disease (eg ... erythematosus [ ... • Infection (eg
Causes of Acute Pericarditis:

Infectious;

Viral: 
Adenovirus 
Coxsackie virus A and B 
Echovirus 
Epstein-Barr virus 
Hepatitis 
Human immunodeficiency
Cardiac injury (e.g ... Pericardial perforation (e.g ... nodosa Rheumatoid arthritis ... Systemic lupus ... erythematosus
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... tissue disorder (e.g ... . systemic lupus ... erythematosus ( ... SLE), rheumatoid arthritis
Differential Diagnosis of Acute Arthritis

Crystal-induced arthritis: Calcium oxalate, gout, cholesterol, pseudogout, hydroxyapatite crystals

Infectious arthritis: Bacteria, fungi,
Crystal-induced arthritis ... : Behçet syndrome ... sarcoid, systemic lupus ... erythematosus,* ... spondyloarthropathy (e.g
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
SLE (systemic lupus ... erythematosus) ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g