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diagnosis differential causes rheumatology algorithm management constipation erythematosus sle systemic abscess activation anemia anomalies anomaly arms bleeding bruising cerebritis children
Characteristic features of the rash are: -Rough texture (like sandpaper) -Worse in the skin folds e.g. groin, axilla,
the skin folds e.g ... ) #Clinical #Dermatology ... #Peds #Pediatrics
Causes of Pediatric Constipation - Differential Diagnosis Algorithm Dietary / Functional: • Insufficient Volume / Bulk Neurologic: •
Causes of Pediatric ... Withholding • Painful (e.g ... Guillain-Barré Syndrome ... Algorithm #Causes #Peds ... #Pediatrics
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Developmental Delay - Differential Diagnosis Algorithm Isolated Domain Delay - Reduced Respiratory Drive: • Cognitive
Teratogenic Disorder (e.g ... Landau-Kleffner Syndrome ... • Mechanical (e.g ... Algorithm #Causes #Peds ... #Pediatrics
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Diagnosis of Lupus ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Causes of Congenital Anomalies - Differential Diagnosis Algorithm Malformation • Embryonic development failure or inadequacy (often multifactorial) Deformation
normal tissue (e.g ... of Anomalies (Syndromic ... • Association (e.g ... Algorithm #Causes #Peds ... #Pediatrics
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Shrinking lung syndrome ... vein thrombosis Hematologic
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
SLE (systemic lupus ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g ... Bruising #Causes #peds
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... Diagnosis #Management #Hematology
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