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differential causes rheumatology algorithm management constipation erythematosus sle systemic abscess activation anemia anomalies anomaly bleeding bruising cerebritis children classification cns
Causes of Pediatric Constipation - Differential Diagnosis Algorithm Dietary / Functional: • Insufficient Volume / Bulk Neurologic: •
Causes of Pediatric ... - Differential Diagnosis ... Withholding • Painful (e.g ... Guillain-Barré Syndrome ... Algorithm #Causes #Peds
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... #hematology #anemia
Causes of Developmental Delay - Differential Diagnosis Algorithm Isolated Domain Delay - Reduced Respiratory Drive: • Cognitive
- Differential Diagnosis ... Teratogenic Disorder (e.g ... • Mechanical (e.g ... Algorithm #Causes #Peds ... #Pediatrics
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Causes of Congenital Anomalies - Differential Diagnosis Algorithm Malformation • Embryonic development failure or inadequacy (often multifactorial) Deformation
normal tissue (e.g ... of Anomalies (Syndromic ... • Association (e.g ... Algorithm #Causes #Peds ... #Pediatrics
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Erythematosus #Diagnosis
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
SLE (systemic lupus ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g ... #pediatrics #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... tissue disorder (e.g ... . systemic lupus ... Cryoglobulins #diagnosis ... classification #rheumatology
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