10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... #SLE #CNS #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... • Systemic lupus ... (eg, systemic juvenile ... [SLE], AOSD) • ... Infection (eg,
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... May be 10 (eg direct ... damage from systemic ... #Classification ... #Proteinuria #Nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... • Malignancy (e.g ... Endocrine disorders (e.g ... #Systemic #Lupus
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
inhibitors, hepatorenal syndrome ... Secondary GNs: Due to systemic ... e.g. ... Post-infectious GN, Lupus ... Differential #Diagnosis #nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... ; e.g. narcolepsy ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis #neurology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... tissue disorder (e.g ... . systemic lupus ... diagnosis #types #classification
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
(systemic lupus ... Congenital heart disease ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... presentations and disease ... of Circulatory System ... - Compartment syndrome
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... sympathetic + ADH activation ... Classification: ... liver insult (e.g ... #Hepatology #Nephrology