17 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... May be 10 (eg direct ... damage from systemic ... #Classification ... #Proteinuria #Nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... (CNS) dysfunction ... (eg, systemic juvenile ... erythematosus [SLE ... • Infection (eg
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... #CNS #neurology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... : Due to systemic ... e.g. ... Differential #Diagnosis #nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... ; e.g. narcolepsy ... pain • Extra-CNS ... autoimmune disorders (Systemic ... Manifestations #diagnosis #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... • Malignancy (e.g ... Endocrine disorders (e.g ... Chronic B-cell activation
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
central nervous system ... (CNS) involvement ... and less common diseases ... infections • Lyme disease ... skull neoplasms (e.g
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Leukemia • MPN/MDS ... B-cell lymphomas), Systemic ... , Behcet disease ... , Sarcoidosis, SLE ... : e.g.
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Autoimmune diseases ... : - 10% SLE or ... tissue disorder (e.g ... diagnosis #types #classification
Indications for Head CT before LP:
 • Age > 60
 • Immunocompromise (e.g., HIV)
 • History
Immunocompromise (e.g ... central nervous system ... (CNS) disease ... risk of having a mass ... #Indications #neurology