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diagnosis differential erythematosus lupus management sle systemic activation acute aki antibodies associations autoantibodies autoimmune bee causes cerebritis conditions extrarticular hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
SLE Anti-SSA (Ro ... La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... : Disease process ... or drugs e.g. ... AIN) • Drugs (e.g
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... (AQP4-lgG disease ... ; e.g. narcolepsy ... pain • Extra-CNS ... Manifestations #diagnosis #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... #neurology #rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
nervous system (CNS ... and less common diseases ... infections • Lyme disease ... skull neoplasms (e.g ... #neurology #noninflammatory
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... (eg, systemic juvenile ... • Infection (eg ... #Rheumatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... • Acute stroke syndromes ... : - Anti-Ro/SSA ... electromyographic (EMG ... Differential #Diagnosis #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... and CNS • Headache ... Erythematosus #Diagnosis #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... - SLE Neurologic ... , Vasculitis (e.g ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... Antisynthetase syndrome ... nucleotidase 1A (Anti cN ... Myositis #Myopathy #rheumatology
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