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diagnosis differential hematology algorithm treatment barre erythematosus guillain lupus nephrology systemic workup activation anesthesia anesthesiology antibodies associations autoantibodies bcnie bloodculture
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... Goodpasture's syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... #CNS #neurology ... #rheumatology #
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Neuroleptic malignant syndrome ... (e.g. haloperidol ... • Serotonin syndrome ... Anticholinergic syndrome ... Sympathomimetic syndrome
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... - SLE Neurologic ... disease, Vasculitis (e.g ... , Behçet's syndrome
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Arthritis • SLE ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... (MPA) • SLE ... Protein deposition (eg ... #Proteinuria #Nephrology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... underlying disease (eg ... • Infection (eg ... hypersensitivity syndromes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... cryoglobulinemia syndrome ... 20% Sjögren's syndrome ... tissue disorder (e.g
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... Endocrine disorders (e.g ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
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