13 results
diagnosis management infectiousdiseases antifungal candida pharmacology treatment antibiotics fungal auris candidemia candidiasis infections invasive overview polyenes review abelcet ambisome amphoterecinb
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Antibiotics • Empiric: Echinocandins ... treatment #fungal #fungemia
Candida Glabrata Species of Candida Most Commonly Isolated in Bloodstream Infections • Symptomatic mucosal infection is detected
disseminated infections (fungemia ... option, consider echinocandin ... diagnosis #management #fungemia
Antifungal Echinocandins - Antibiotics Class Overview Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... monotherapy) All Echinocandins ... Review #Overview #Echinocandins
Antibiotics and CNS Diffusion 1. Drugs with good CNS diffusion: - Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole 2. Drugs
infections: - Echinocandins
Antifungal Coverage Activity Antibiogram Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Triazoles #Polyenes #Echinocandins
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview Mechanism: binds ergosterol in membrane and
infections – because echinocandins
Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample •
with AFST) • Echinocandin
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Disseminated infection; Fungemia
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
aminoglycosides, echinocandins
Pulmonary Histoplasmosis Quick Facts on Histoplasma capsulatum: • Dimorphic fungi, in yeast phase within the body •
• Resistant to echinocandins
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