18 results
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding risk ... HAS-BLED schemas #Diagnosis ... #Hematology #CHADS2 ... Comparison #Score #Risk ... Stroke #Bleed #Anticoagulation
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
clinical benefit of anticoagulation ... of withholding anticoagulation ... #Calculators #Anticoagulation ... #Factors #Hematology ... #Diagnosis
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
history of prior venous ... are not a major risk ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Patient risk stratification ... mass index; VTE = venous ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
and bleed risk ... on anticoagulation ... Stroke #Bleed #Anticoagulation ... #AFib #Diagnosis ... #Hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
fatigue; Increases risk ... Potentially increases venous ... arterial thrombotic events ... #Pharmacology #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... • Acquired Risk ... cardiovascular risk ... #Arterial #pathophysiology ... #hematology #differential
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... blood donor • Pathophysiology ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
clot #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology ... #anticoagulation
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
- Any adverse events ... Stable patients ... Anticoagulation ... postoperative cardiac events ... stratification #diagnosis