70 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Non malignant hematologic ... conditions: • Rebound effect ... ITP • Rebound effect ... Thrombocytosis #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... anemia, Rebound effect ... Lymphoma, Rebound effect ... Thrombocytosis #Platelets #Differential
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... Extrinsic RBC Defects ... : Membrane defects ... Hemolytic #Anemias #Differential ... Diagnosis #Algorithm #hematology
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
vasculitis can affect ... predominantly affects ... predominantly affects ... #Diagnosis #Rheumatology ... #Differential #
Molluscum Contagiosum 
Clinical 
 • Most common in school-age children 
 • Transmitted by direct contact
• Typically affects ... extremities • Spares ... Clinical #Management #Dermatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Non-immune: Membrane Defects ... - Hemoglobin Defects ... #Hemolysis #Differential ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis - Differential ... Hgb - Membrane Defects ... - RBC Enzyme Defects ... Extravascular #Differential ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet Defects ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
• Generally affects ... necrosis: • Affects ... • Differentiate ... SickleCell #Disease #differential ... diagnosis #causes #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... , Other enzyme defects ... Unstable hemoglobin defects ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology