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differential antibodies classification joint pain acute aki ana antineutrophil antinuclear associated associations autoantibodies canca causes conditions cryoglobulinemia cryoglobulins dermatology extrarticular
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
associated with PR3+ antibody ... associated with MPO+ antibody ... PR3 Anti-GBM disease ... MPO #PR3 #Diagnosis ... #Rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... StanfordChiefs #ANCA ... #diagnosis #algorithm ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... Vasculitis: • ... + 60% • Eosinophilic ... #antibodies #diagnosis ... #rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
c-ANCA - Vasculitis ... - Vasculitis, e.g ... Endomyseal antibody ... #diagnosis #table ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • EGPA: - Eosinophilia ... Differential Diagnosis ... purpura: strong sign ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... #Rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Amyloidosis • Eosinophilic ... Antiphospholipid-antibody ... syndrome • Vasculitis ... #differential #diagnosis ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... life-threatening diseases ... antibody, Anti-GBM ... antibody • Urine
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... clinical context and signs ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... Interstitial nephritis: eosinophilia
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