21 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... in drug-induced SLE ... + 60% • Eosinophilic ... #antibodies #diagnosis ... #rheumatology #
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (MPA), and eosinophilic ... associated with PR3+ antibody ... associated with MPO+ antibody ... MPO #PR3 #Diagnosis ... #Rheumatology
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... StanfordChiefs #ANCA ... #diagnosis #algorithm ... #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... antibody), dsDNA ... • Scleroderma (Systemic ... Vasculitis: P-ANCA ... #diagnosis #associations
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Vasculitis, e.g ... granulomatosis p-ANCA ... - Vasculitis, e.g ... Associations #diseases #diagnosis ... #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... • EGPA: - Eosinophilia ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
A Antinuclear Antibody ... (ANA) M Mucositis ... #IMDAMNSHARP #sle ... #systemic #lupus ... erythematosus #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... diseases, such as SLE ... purpura: Strong sign ... Polyangiitis): • Eosinophilia ... #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Amyloidosis • Eosinophilic ... Antiphospholipid-antibody ... syndrome • Vasculitis ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... erythematosus (SLE ... erythematosus (SLE ... #patterns #rheumatology ... #diagnosis #differential