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differential causes hyponatremia acute microscopy nephrotic proteinuria aki glomerular glomerulonephritis hematuria lupus management nephritic renal sle sodium ain associated biopsy
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
/nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Algorithm #Nephrology ... #Diagnosis
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Urine Microscopy ... “urine poker quads ... #Casts #Urine # ... Microscopy #Clinical ... #Nephrology #Sediment
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... #Nephrotic #Syndromes ... #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... tubular proteinuria, granular ... casts/RTE; blend ... sediment • Received ... #nephrology #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... Granular - May ... syndrome ("Maltese ... Differential #Microscopy #Diagnosis ... #Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... ) • Granular Casts ... #nephrology #interpretation ... #diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
- Diagnostic approach ... urine sediment ... , WBC casts) especially ... #diagnosis #algorithm ... #sle #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Algorithm Persistent ... • Fanconi's syndrome ... RBC casts ... #Proteinuria #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... Algorithm Red ... blood cells on urine ... RBCs and/or RBC casts ... #Algorithm #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... microscopy / urinary sediment ... investigations depending on clinical ... • Interstitial nephritis ... #nephrology #causes
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