31 results
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... of mb granular casts ... Granular #MuddyBrown #Casts ... #Clinical #Nephrology ... #Sediment
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... sediment - WBC/ ... RBC casts ... #Proteinuria #Nephrology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... proteinuria, granular casts ... /RTE; blend sediment ... #nephrology #diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... #Urine #Microscopy ... #nephrology #interpretation
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
• White cell casts ... disease • Granular casts ... crystals may indicate metabolic ... key #diagnosis #nephrology ... #casts
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Differential Diagnosis Algorithm ... hyperaldosteronism • Low Urine ... (late) • High Urine ... #Nephrology #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... microscopy / urinary sediment ... investigations depending on clinical ... Differential #Diagnosis #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
sediment Microscopic ... sediment by microscopy ... pain hematuria syndrome ... hematuria: - RBC casts ... #urology #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... repeat testing • Acute ... proteinuria, RBC casts ... → Refer to Nephrology ... if cause not identified