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differential neurology management physicalexam treatment hyponatremia microscopy acute alkalosis gunn hematuria hypokalemia jaw marcus metabolic nephrotic ophthalmology phenomenon proteinuria wink
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... of mb granular casts ... Granular #MuddyBrown #Casts ... #Clinical #Nephrology ... #Sediment
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... RBC casts ... #Proteinuria #Nephrology ... #Algorithm #Causes
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... sediment Microscopic ... sediment by microscopy ... hematuria: - RBC casts ... #nephrology #renal
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic sydnrome ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... proteinuria, granular casts ... /RTE; blend sediment ... #nephrology #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... and Differential Diagnosis ... microscopy / urinary sediment ... investigations depending on clinical ... #nephrology #causes
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... Algorithm • Confirm ... proteinuria, RBC casts ... → Refer to Nephrology ... #Algorithm #Workup
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Algorithm Red ... blood cells on urine ... RBCs and/or RBC casts ... #Algorithm #Causes
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