15 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... #Thrombotic ... #Comparison #Diagnosis ... #Table #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... Thrombocytopenic ... Purpura (TTP) ... Microangiopathy #TMA #hematology ... differential #diagnosis #HUS
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... thrombotic thrombocytopenic ... How to approach thrombocytopenia ... , Hematology 2012
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic ... HUS), Serum creatinine ... HUS) Treatment ... Thrombotic #Thrombocytopenic ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... HELLP Syndrome • TTP ... /HUS • DIC • ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
hemolysis: • Thrombotic ... microangiopathies (TMA) - TTP ... known as atypical HUS ... macroangiopathic hemolytic anemia ... differential #diagnosis #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... triad of MAHA + thrombocytopenia ... @AnnKumfer #Thrombotic ... Microangiopathy #TMAs #hematology ... #hus
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... /HUS, HELLP Syndrome ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disease - DIC/TTP ... /HUS - Hemolytic ... anemia - Splenomegaly ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... differential #diagnosis #hematology ... #anemia