20 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Vesicopustule on erythematous ... Hypersensitivity vasculitis ... #skin #rashes #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... rashErythematous ... permanent alopecia Differential ... Chronic B-cell activation
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... ANCA associated vasculitis ... (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... Lyme disease, Vasculitis ... Genitourinary system ... system • Mitral ... #joint #pain #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #systemic #erythematosus
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash ... Disorders #msk #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... mucositis - Rash ... lupus erythematosus ... , and SLE) • Urinalysis ... #rheumatology #classification
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... 69% - Malar rash ... #Systemic #Lupus ... #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... cutaneous lupus • Arthritis ... least 2 joints • Neurologic ... #Criteria #SLE
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... rheumatology #diagnosis #differential