964 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
T-Cell mediated; exposure ... several days after exposure ... Initial exposure ... Allergy #Immunology #pathophysiology
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
(occurs at the exposed ... Radiology #Clinical #Pathophysiology
Innate Immune Cells - Pathophysiology
The innate immune system consists of granulocytes, mast cells, natural killer cells,
Immune Cells - Pathophysiology ... previous pathogen exposure ... Immune #Cells #Pathophysiology
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
Environmental exposure ... #Pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
symptoms after exposure ... Hypotension after exposure ... #Anaphylaxis #pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Sensitization -> Antigen Exposure ... minutes of antigen exposure ... minutes) Antigen Exposure ... Rhinitis #Rhinorrhea #pathophysiology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
- Proptosis -> Exposes ... Orbital #Cellulitis #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Allergen: Initial exposure ... allergen Second Exposure ... Allergy #Immunology #pathophysiology
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
, stress, cold exposure ... and menses • Pathophysiology
Cardiac Myocyte Contractile cycle
 - Ca2+ binds to TnC → TnI is inhibited → conformational change
tropomyosin that exposes ... #Pathophysiology