21 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... typically prolong PT ... Prolonged PT and ... #Abnormal #PT
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... , FVII, FIX, FX) ... #Abnormal #PT
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time (PT ... Thromboplastin Time (PTT ... Prothrombin Time (PT ... warfarin) • Factor VII ... thematttsai #PT
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
12-13 g/dL, • ANC ... iron studies, PT ... /aPTT Differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
== NORMAL PT ... level NORMAL PT ... If the PT remains ... evaluation of factor VII ... Inherited: • Factor VII
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... levels of factors VII ... Fibrinogen: ↓ • PT ... INR < 2.3 - APTT
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
complexes with FVIIa ... TF-FVIIa also activates ... thrombin #clot #PT ... #PTT #diagnosis
Mitral Valve Endocarditis on POCUS Echocardiogram
66 yo presents with petechiae to lower extremities. Pt had mitral
Pt had mitral valve ... clinical #cardiology #a4c
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
you see on this SC ... one month ago-pt ... clinical #cardiology #s4C
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Pt had extensive ... Echocardiogram #A4C