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diagnosis management differential rheumatology lupus coagulation druginduced oncology sle table treatment antiphospholipid apls aptt biliary bleeding bruising cholangitis cirrhosis classification
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... factor activity ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... venipuncture sites Laboratory ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... deficiency Work ... #Causes #dermatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... druginduced #lupus #sle #comparison
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
patientsl • Risk factors ... without other cause ... patients • Risk factors ... Transfusion #Reactions #hematology ... #diagnosis #comparison
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... von Willebrand factor-cleaving ... decrease in most cases ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
versus DIL • Laboratory ... - CRP: Usually normal ... • Immunologic Workup ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Idiopathic • Normal ... differential #diagnosis #algorithm ... #rheumatology
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