16 results
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... factor activity ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... PT/INR • Normal ... prolonged if very low factor ... VIII) Treatment ... Disease #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... venipuncture sites Laboratory ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
patientsl • Risk factors ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... • Immunologic Workup ... druginduced #lupus #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
versus DIL • Laboratory ... - CRP: Usually normal ... • Immunologic Workup ... life-threatening • Treatment ... Management #Summary #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Thrombocytopenia - Abnormal ... deficiency - Abnormal ... deficiency Work ... #Causes #dermatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... relapse No specific laboratory ... antibodies, rheumatoid factor ... management #phenotypes #workup ... #treatment #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... von Willebrand factor-cleaving ... levels - Usually normal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology