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diagnosis management hepatology rheumatology cirrhosis differential hepatitis pbc summary table treatment aih autoimmune biliary causes coagulation liver lupus oncology primary
COVID-19: ICU Guidelines for the Non-Intensivist Infection Control Risk Factors for Severe Disease Initial Laboratory Workup COVID-19 Specific Medications Respiratory Cardiac Hematologic Neuro/Sedation #COVID19 #ICU
Infection Control Risk Factors ... for Severe Disease ... Initial Laboratory ... Workup COVID-19 ... Respiratory Cardiac Hematologic
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... Cholangitis #pathophysiology ... #pbc #psc #hepatology ... #comparison
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Environmental Risk Factors ... Epigentics Risk Factors ... female-predominant disease ... of autoimmune disease ... #hepatology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
(warfarin) • Factor ... inhibitor • Liver disease ... test tubes • Factor ... Thromboplastin #laboratory ... #hematology #diagnosis
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Deficiency of Factor ... Malabsorption (e.g. celiac disease ... Advanced Liver Disease ... Summary #table #comparison ... #diagnosis #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... GI. uterine) Laboratory ... prolonged if very low factor ... VonWillebrand #Disease ... #Diagnosis #Hematology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease Increased Thrombosis Increased Platelet-Vesset Wall Interaction •
Bleeding in Liver Disease ... von Willebrand factor ... Generation • Incr Factor ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Consumption of Clotting Factors ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... • Severe Liver Disease ... treatment #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... SOAP) - Risks factor ... PT, aPTT(liver disease ... Diagnosis #Causes #Workup ... #hematology
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