7 results
diagnosis differential hematology causes management thrombocytosis anemia bronchiectasis endocrinology ferritin hemophagocytic hlh iron lymphohistiocytosis pediatrics platelets shortstature stills
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
mevalonate kinase deficiency ... hepatitis • Pulmonary ... Prunelle Getten #AdultOnset ... diagnosis #management #treatment ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Acute hemolysis, deficiency ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... , Celiac disease
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Differential Diagnosis Algorithm ... athletic training, Pulmonary ... Structural: Celiac disease ... Tropical sprue, IBD ... #ferritin #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Inflammatory: • IBD ... disorders • Celiac disease ... effect following treatment ... malignancy • Iron deficiency ... #Causes #Hematology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... • GH Deficiency ... Panhypopituitarism Treatment ... Celiac, IBD) • ... Cystic Fibrosis,
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... • Autoimmune diseases ... Cellular immune deficiency ... Unknown cause Treatment ... #summary #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Bronchiectasis - Summary ... Causes: • Cystic fibrosis ... , in advanced disease ... α1-antitrypsin deficiency ... mycobacteria Treatment
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