54 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Reticulocytes • Abnormal ... #Anemias #Differential ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
with Normal Mean ... PRV, Chronic) Normal ... Polychromatic Macrocytes, Normal ... - Abnormal RBCs ... Hemoglobinopathy - Normal
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... anemia • ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... Normal Blood Smear ... Target Cells, Normal ... WBCs - Normal ... Deficiency - Abnormal
Hoffmann's Sign

Hoffman's sign means upper motor neuron injury.  The Hoffmann's reflex test itself involves loosely
holding the middle finger ... allowing the middle finger ... Reflex #Positive #Abnormal ... #clinical #video ... #neurology #physicalexam
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease Normal ... • Bleeding • Hemolysis ... #Causes #Hematology
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
Hoffman's sign. ... #Hoffmanns #Sign ... Reflex #Positive #Abnormal ... #clinical #video ... #neurology #PhysicalExam
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects: Sickle cell anemia ... Blood Smear ↑ abnormal ... Diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Deficiency) Ferritin normal ... decreased, TIBC normal ... increased, Serum iron normal ... , TIBC Normal - ... Increased HgbA2, Normal
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... products or D-dimer - Normal ... anemia Indirect ... WBC count and differential ... #Workup #Hematology