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differential management hematology clinical rheumatology oncology algorithm skin symptoms syndrome classification dermatomyositis leukemia pathology pathophysiology pulmonary rash skinrash syndromes thrombocytosis
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
insufficiency • Vasculitis ... Mycosis fungoides (cutaneous ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology ... #Algorithm #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... aphthous ulcers, cutaneous ... purpura: strong sign ... of cutaneous leukocytoclastic
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... suspected: • Signs ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... nose, ears, or fingers ... presentation) • Cutaneous ... anemia • Cold ... #hematology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... tract, and often causes ... episcleritis as well as inner
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Rheumatologic, Vasculitides ... , IBD, Celiac disease
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... ) • Cutaneous Lesions ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #management #signs
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