41 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... Blood #Disorders #hematology ... #Markers #Differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... malignancies • Anemia ... myeloid leukemia (CML ... #Differential # ... Diagnosis #Causes #hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... #Differential # ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... Iron deficiency anemia ... #Differential # ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... basophilia, and thrombocytosis ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Platelet Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... #Platelets #Differential
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Increased red cell ... Increased red cell ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... Causes #Workup #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... • Neutropenia, anemia ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Microangiopathic Hemolytic Anemia ... autoimmune hemolytic anemia ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... vera, essential thrombocytosis ... Disease • Sickle Cell ... Spleen #Enlarged #Differential ... Algorithm #Causes #Hematology