20 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... modify immune function ... reabsorption in Proximal, loop ... #pathophysiology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... Thick ascending loop ... #Localization #Nephron ... #Defects #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... limb of Henle's loop ... #Pathophysiology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Hypercalcemia-PTH effect ... Magnesium #Low #Causes
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB effects ... NSAIDs cause vasoconstriction ... normal kidney function ... use shouldn't cause ... Nephrology #Renal #Pathophysiology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Altered Renal Function ... Direct effect to ... excretion in distal nephron ... AngiotensinII #Pathophysiology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Differential Diagnosis Algorithm ... Weakness • Motor Neuron ... Neuromuscular Junction ... #Causes
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... kidney), which causes ... drugs include side effects ... Side effects include ... have good kidney function
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... transport, renal function ... Gastrointestinal function ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Differential Diagnosis Algorithm ... Disease Motor Neuron ... Neuromuscular Junction ... #Causes