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management syndrome differential lupus symptoms algorithm disease systemic classification erythematosus oncology arthritis causes hepatology vasculitis comparison dermatology druginduced hemophagocytic hepatopulmonary
Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Erythematosus (SLE ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Glucocorticoids, IL-1B, ATRA ... #Algorithm #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment ... Management #Summary #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
, holster sign, ... at diagnosis). ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... arterial HTN) ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
calculators - HAS-BLED (atrial ... validated for VTE treatment ... studies suggest net clinical ... Anticoagulation #Factors #Hematology ... #Diagnosis
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Systemic Lupus (SLE ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
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