30 results
Pathophysiology, Signs and Symptoms of Hemolytic Anemia

#Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... and Symptoms of Hemolytic ... Anemia #Pathophysiology ... #Hemolytic #Anemia
Hemolytic anemia in Wilson's disease

#Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
Hemolytic anemia ... Wilsons #Disease #hemolytic ... #anemia #Hematology ... #pathophysiology
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... of Hemolytic Anemia ... environment #Pathophysiology ... #Hemolytic #Anemia
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... AIHA • Anemia ... #Anemia #diagnosis ... #management #treatment
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... AIHA #Autoimmune #Hemolytic ... #Anemia #Pathophysiology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... Hemorrhage or hemolysis ... elevated, but anemia ... but undiagnosed, folate ... #VitaminB12 #Folate
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... Sideroblastic anemia ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Megaloblastic: Folate
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Vitamin B12 or Folate ... Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA # ... Treatment #management
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Index < 2: • Anemia ... , Vitamin B12, Folate ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... anemia, Intrinsic