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diagnosis differential aflp comparison dermatology hellp intravascular obstetrics palpable petechiae pregnancy table algorithm anemia arterial blanching bruise dic disseminated ecchymosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... inflammation • Thrombocytopenia ... Platelet defects • Coagulation ... : - Thrombocytopenia ... palpable #nonpalpable
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... → Palpable • Thrombocytopenia ... HIT, ITP/HUS), Coagulation ... #nonpalpable #palpable ... #Causes #Differential
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Thrombocytopenia ... presents with coagulation ... child * Severe cases ... #Pregnancy #TTPHUS ... Obstetrics #OBGyn #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Thrombocytopenia ... presents with coagulation ... child * Severe cases ... #TTPHUS #HELLP ... AFLP #obstetrics #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
non-blanching, nonpalpable ... individuals with thrombocytopenia ... ecchymosis) is caused ... are typical of coagulation ... Measurement of coagulation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... differential #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemostasis: - Thrombocytopenia ... Henoch Schonlein Purpura ... Non-Palpable Rash: - Purpura ... Complete blood count coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Heparin-induced thrombocytopenia ... intravascular coagulation ... and other causes ... of purpura fulminans ... pathophysiology #hematology
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