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diagnosis hepatology differential lfts interpretation bilirubin gastroenterology hematology hyperbilirubinemia laboratory transaminitis anemias bleeding bruising causes chemistry congenital endocrinology enzymes function
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... vs bone Bili - Direct ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct ... Differential #Diagnosis #Algorithm
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... bilirubin (TBili) Direct ... bilirubin (Conjugated ... Indirect bilirubin ... (Unconjugated)
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... Half-life: 1 week • Direct ... function may be abnormal ... Enzyme Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... life: 1 week • Direct ... or amyloid: • Elevation ... Enzyme Elevation ... blood cells Unconjugated
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... Failure - Elevated conjugated ... and unconjugated ... ALT and AST - Elevations ... fold with acute liver
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of about 30% of normal ... of hemolysis or liver ... an increase in conjugated ... the blood • Defect ... • Increase in conjugated
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... • ↑ LDH • ↑ Indirect ... / unconjugated ... Reticulocytes • Abnormal ... Differential #Diagnosis #Algorithm
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... magnitude of enzyme elevation ... #Algorithm #Hepatology
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