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diagnosis differential hepatology hematology bruising lfts transaminitis amyloid amyloidosis anemia bilirubin chemistry classification conjugated gastroenterology genital gynecology hemostasis hepatitis hyperbilirubinemia
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... vs bone Bili - Direct ... #FunctionTest # ... LFTs #Elevation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Half-life: 1 week • Direct ... Enzyme Elevation ... RBC (hemolysis, bleeding
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
dabigatran, argatroban, direct ... PT/ABNORMAL PTT ... discern these causes ... are liver function ... Anticoagulants (warfarin, direct
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... life: 1 week • Direct ... or amyloid: • Elevation ... Enzyme Elevation ... RBC (hemolysis, bleeding
Causes of Abnormal Genital Bleeding - Differential Diagnosis Algorithm Non-Gynecologic: • Medical (e.g. coagulopathy, liver disease, renal
Causes of Abnormal ... Genital Bleeding ... Differential Diagnosis Algorithm ... coagulopathy, liver ... #Causes #OBGyn
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... #Causes #Hematology
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... hypertension; some normal ... • Paroxysmal elevations ... when paroxysmal elevations ... mellitus) are directly
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Proteinuria • Can detect ... failure • GI bleeding ... hypoadrenalism • Nausea ... Doppler imaging: Normal-size ... Diagnostic imaging of liver
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