20 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False Elevation ... HbA1c == False Elevation ... • Asplenia Laboratory ... HbA1c #HgbA1c #Laboratory ... Diagnosis #DM2 #Differential
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs) Elevation ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation ... Transaminitis #diagnosis #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Mild-to-moderate decrease ... Mild-to-moderate elevation ... WBC count and differential ... Diagnosis #Workup #Hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Hypoalbuminemia - Decreased ... ALT and AST - Elevations ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
or normal) • Elevation ... : Elevated • Decreases ... Scoring #diagnosis #hematology ... #laboratory
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Fragility: • Decreased ... mountain spotted fever ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... without platelet decrease ... bartonella (oroya fever ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Hyperferritinemia - Differential ... Decreased hepcidin ... Hematologic Malignancy ... saturation to differentiate ... extreme ferritin elevation
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Hyperferritinemia, decreased ... fraction < 20% Differential ... management #treatment #rheumatology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Emergencies - Differential ... Diagnosis Framework HEMATOLOGIC ... death Neutropenic Fever ... • Vomiting, decreased ... emergencies #oncology #differential