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diagnosis differential lfts transaminitis alp bilirubin chemistry enzymes gastroenterology hepatitis hepatocellular injury interpretation laboratory phosphatase tests abnormal alkphos astalt bleeding
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... vs bone Bili - Direct ... #FunctionTest # ... LFTs #Elevation ... Transaminitis #diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Differential #Diagnosis #Algorithm ... #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Injury • AST/ALT elevation ... + ULN ALT) / (alkaline ... phosphatase + ULN alkaline ... #differential #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Interpretation Alanine ... , lungs, RBCs Alkaline ... bilirubin (TBili) Direct ... Indirect bilirubin ... Interpretation #diagnosis #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct ... gastroenterology #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Tests - AST, ALT, Alkaline ... Alkaline phosphatase ... hepatocyte - Elevation ... AlkPhos #Bilirubin #Hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... compared with alkaline ... disproportionate increase in alkaline ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Low Alkaline Phosphatase ... synthesized in: liver ... eliminated • Elevation ... phosphate &/or • Elevation ... Hyophosphatasia #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... life: 1 week • Direct ... or amyloid: • Elevation ... Enzyme Elevation ... #differential #Hepatology
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