19 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... urearetics) 3) Loop ... agents (eg, furosemide ... Adenosine #Nephron ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... mannitol) 3) Loop ... Diuretics (e.g. furosemide ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... reabsorption in Proximal, loop ... distal component of Nephron ... absorption in distal nephron ... decreased renal blood flow
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... • HTN Absent: Loop ... Differential #Diagnosis #Algorithm ... #low #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Differential Diagnosis Algorithm ... • Diuretics (loop ... aldosteronism Low ... Renin, Low Aldosterone ... Differential #Diagnosis #Algorithm
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... • Bumetanide, Furosemide ... loss through the nephron ... nephrology #conversion #loop ... #thiazide #classes
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis Algorithm ... Primary polydipsia, Low ... Helbert Rondon, MD @NephroMD ... #differential #algorithm ... #causes #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Hypomagnesemia #Magnesium #Low ... #Diagnosis #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... B-Cell ~90% • Low ... Classification #pathophysiology ... #differential #algorithm