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diagnosis hematology differential sle causes erythematosus algorithm heparin hit oncology systemic treatment comparison druginduced hemeonc intravascular mimickers purpura reactions signs
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management - HIT Suspected - Calculate 4T Score
Heparin Induced ... Thrombocytopenia ... Diagnosis and Management ... #Thrombocytopenia ... #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... - Hemolytic anemia ... Mimickers: Drug-induced ... #differential #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... NEUROLOGIC - HEMOLYTIC ANEMIA ... (<1000/MM3) - THROMBOCYTOPENIA ... absence of hemolytic anemia ... #Diagnosis #Rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
following EtOH induced ... thrombocytopenia ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
purpura, Heparin induced ... thrombocytopenia ... Autoimmune Hemolytic anemia ... , Penicillin-induced ... • Ex: Systemic Lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... ) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia ... #Lupus #SLE #systemic ... symptoms #diagnosis #rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Platelet count reduced ... SLE (systemic lupus ... - Fanconi anaemia ... - Aplastic anaemia ... - Drug-induced
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Great Mimickers - SHALLOTS Mnemonic S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
dermatitis, dementia, anemia ... , thrombocytopenia ... anything L - Lupus ... pleuritis, drug-induced ... Could be lupus in
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... microangiopathy: Thrombotic thrombocytopenic ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology ... #anemia
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