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Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,

Pathophysiology #GI ... #IM #NASH #NAFLD ... NonAlcoholicFattyLiverDisease #NEJM

Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
- Heliotrope sign and edema
- Nail-fold changes
-

- Heliotrope sign ... or shawl sign ... - Gottron's sign ... scale - Holster sign ... vasculopathy of the GI

Osteoporosis: Pathogenesis and risk factors

• Age > 30 (post-peak bone mass)
• Post-menopausal women ->

Leukemia) • GI ... pathophysiology #signs

Upper endoscopy revealed a pigmented mass in the duodenal bulb (Panel A) and two additional masses

B) #Clinical #GI ... #Derm #Honc #Melanoma ... EGD #Metastatic #NEJM

IgM and Non-IgM - Risk and Type of Progression #EBM #Honc #MGUS #Progression #IgM #NonIgM #MultipleMyeloma

IgM and Non-IgM ... Progression #EBM #Honc ... #Progression #IgM ... MultipleMyeloma #NEJM

Opportunistic Infections in HIV/AIDS
Here's a little symptom-based guide to OIs in pts with HIV I made

- Pulmonary - GI ... Guide #Symptoms #Signs

Colchicine Toxicity
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs
• Severe GI distress

hrs • Severe GI ... Toxicology #Symptoms #Signs

Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is

or swelling - GI ... Non-specific abdo pain, GI ... Pathophysiology #Diagnosis #Signs

Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal

Anaphylaxis: Signs ... • persistent GI ... phase symptoms Signs ... immunology #diagnosis #signs

Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
- General - From asymptomatic to myxedema coma, “Like

- Symptoms and Signs ... hypertension - GI ... Palpitations, Afib - GI ... Hyperthyroid #Symptoms #Signs

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