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hematology causes workup management erythematosus hemolytic systemic oncology syndrome antinuclear classification hemolysis pancytopenia autoantibodies dermatology disorders leukemia nephrology vasculitis approach
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Autoimmune • ITP • SLE ... Alloimmune • anti-HLA antibodies ... Diagnosis #Algorithm
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
Glomerulonephritis (GN ... cytoplasmic antibodies ... ; SLE, systemic ... lupus erythematosus ... Glomerulonephritis #Algorithm
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Neurological 12% - Thrombocytopenia ... - Hemolytic anemia ... Auto-Antibodies ... Diagnosis and Lupus ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... (<1000/MM3) - THROMBOCYTOPENIA ... IMMUNOLOGIC CRITERIA - ANA ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... #diagnosis #algorithm ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... #Antinuclear #Antibodies ... #rheumatology #diagnosis ... #differential
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... and hemolysis: ... Diagnosis #Algorithm ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Rule out B12 and ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Diagnosis Algorithm ... • Anti-GBM antibodies ... (MPA) • SLE ... #Diagnosis #Algorithm
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