24 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal Involvement ... Erythematosus ... #diseases #SLE ... #venn #nephrology ... classification #types #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... & renal involvement ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology #
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
M DAMN SHARP - Lupus ... Arthritis R Renal ... Disease (Nephritis ... #erythematosus ... #rheumatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Cerebrovascular Disease ... #Erythematosus ... #SLE #CNS #neurology ... #rheumatology #
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... thromboembolism, renal ... Post-infectious GN ... , Lupus Acute Tubular ... #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematosus) ... Differential Diagnosis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Chain deposition disease ... S - Systemic Lupus ... Erythematosus ( ... total 50, renal ... CHAMPS #Mnemonic #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Complex: Systemic lupus ... erythematosus, ... #differential #diagnosis ... #nephrology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Abdominal pain (20%) Renal ... disease (30%): ... SLE #systemic #erythematosus ... signs #symptoms #diagnosis ... #rheumatology