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ana testing antibody antibodies causes cytoplasmic hematology nuclear vasculitis anemia autoantibodies classification dermatology erythematosus glomerulonephritis hemolytic mimickers petechiae petechial physicalexam
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Kumfer @AnnKumfer #Antinuclear ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus (SLE ... Kumfer @AnnKumfer #Antinuclear ... #rheumatology # ... diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... : - SLE, SSc ... ARUPLabs #ANA #Antinuclear ... #differential # ... diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Diagnosis Algorithm ... Autoimmune • ITP • SLE ... Diagnosis #Algorithm ... #Causes #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Neurological 12% - Thrombocytopenia ... involvement 3% SLE-Related ... Diagnosis and Lupus ... Lupusreference #SLE ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... : • SLE, SSc, ... : • SjS, SLE, DM ... #differential # ... diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic Patterns ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... hemostasis: - Thrombocytopenia ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... genotypes): SS, SC, SE ... Schistocytes, thrombocytopenia ... #Diagnosis #Algorithm ... #workup #hematology
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