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hematology differential blood nephrology product reactions syndrome treatment vasculitis aki altered apml cerebritis classification crisis dic differentiation disseminated emergencies encephalopathy
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Mental Status (AMS ... - Differential Diagnosis ... : • Acute GN ... Vasculitis • Lupus ... #causes
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Common causes of ... - Differential Diagnosis ... thromboembolism, renal ... Post-infectious GN ... , Lupus Acute Tubular
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS ... to cold IgG • Lupus ... vascular beds-renal ... #Differential #Diagnosis ... #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... (for secondary APS ... #neurology #rheumatology ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... Bleeding (64%) • Renal ... Thromboembolism (7%) • CNS ... #diagnosis #causes ... #treatment #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Rare: DAH, acute ... Renal Failure ... coagulopathy, RRT/IMV as ... #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... : Blast crises ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
intravascular coagulation ... Treat underlying cause ... ) - Symptoms: CNS ... , hypotension, renal ... #HemeOnc #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... tract, and often causes ... chorioretinitis, CNS ... #Rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... , and possibly renal ... mediators such as ... skin (16-32%): lupus ... #Management #Signs
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