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diagnosis management sle differential systemic algorithm ana antibodies antinuclear druginduced patterns summary activation arthritis bcell causes cerebritis classification cns comparison
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm By Matthew Ho, MD PhD @MatthewHoMD #Diffuse
Diffuse large B ... Management and Treatment ... MatthewHoMD #Diffuse ... #Algorithm #oncology ... #hematology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... • Nucleolar: Diffuse ... erythematosus ( ... ANA #patterns #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Erythematosus ... Algorithm #Causes #Hematology ... #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Puncture, EEG Treatment ... #Erythematosus ... CNS #neurology #rheumatology ... diagnosis #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... pneumonitis • Diffuse ... enteropathy, and diffuse ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... life-threatening • Treatment ... #Systemic #Erythematosus ... Management #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Systemic #Lupus ... #Erythematosus ... Summary #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus ( ... erythematosus ( ... • Nucleolar: Diffuse ... erythematosus ( ... ANA #patterns #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... • Class IV - Diffuse ... glomeruli) Diffuse ... Nephritis #Management #treatment ... #management #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Immunotactoid GN ... -C3 GN • Cast ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
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