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diagnosis differential erythematosus systemic sle vasculitis antibodies management glomerulonephritis hematology nephrology patterns rpgn algorithm anca antibody antineutrophil arthritis autoantibodies criteria
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Homogeneous: Systemic lupus ... , Drug-induced Lupus ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Discoid Rash A Antinuclear ... Antibody (ANA) ... sle #systemic #lupus ... erythematosus #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... lupus nephritis ... Lupusreference #Antinuclear ... erythematosus #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... , Drug-induced Lupus ... , Drug-Induced Lupus ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... ) • Systemic lupus ... #Antinuclear #Antibody ... antibodies #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... (ANA) - 95% - Initial ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... low C4, Low C3 and ... #EULARACR #Classification ... Erythematosus #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... (C-ANCA): GPA > ... (P-ANCA): eGPA, ... diagnosis #algorithm #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... Diseases: • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... post-infectious GN ... ) + • c-ANCA: ... staining • p-ANCA ... Glomerulonephritis #RPGN #Classification
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