17 results
diagnosis differential symptoms erythematosus sle syndrome systemic vasculitis hematology management myopathy activation antibodies antinuclear autoantibodies classification comparison disease henochscholeinpurpura hsp
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... , and arthritis ... #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... diagnosis #comparison #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Positive ANA ≠ Autoimmune ... Sjögren Syndrome, Myositis ... Thyroid, Autoimmune ... #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... Autoimmune Diseases ... : • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Autoimmune → Inflammation ... noninflammatory Signs ... • Syphilis - Autoimmune ... Rheumatologic Disease ... Diagnosis #MSK #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Scotoma, Ocular pain ... positive NMO only): Myositis ... , Comorbid autoimmune ... disorders (Systemic lupus ... neurology #symptoms #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... anemia 4% - Myositis ... Auto-Antibodies: - ANA ... autoantibodies #signs ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... : • Joint pain ... • Transverse Myelitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Conjunctivitis, mucositis ... involvement, abdominal pain ... and GN Anti-GBM ... Differential #Diagnosis #Rheumatology
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