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diagnosis differential erythematosus systemic syndrome disease dermatology signs summary symptoms classification comparison druginduced hemophagocytic hlh lymphohistiocytosis msk neurology rheumatoid thrombocytopenia
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and ... Associated with Joint ... Pain Eyes ... #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... of hip (rare), Arthritis ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... • SLE • Psoriatic ... Symmetrical: • RA • SLE ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... and/or joint aches ... diagnosis #comparison #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... : • Joint pain ... arthropathy • 90% joints ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Workup: - ANA ... life-threatening • Treatment ... #Summary #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... in at least 2 joints ... low C4, Low C3 and ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... pain / swelling ... imaging Treatment ... #diagnosis #management ... #rheumatology
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