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diagnosis differential management erythematosus syndrome joint antibodies monoarthritis monoarticular pathophysiology patterns polyarthritis polyarticular sjogrens vasculitis workup activation algorithm aortitis approach
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... (SLE), Systemic ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #patterns #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... Antibody (ANA) ... R Renal Disease ... #IMDAMNSHARP #sle ... #systemic #lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... (20%) Renal disease ... #SLE #systemic ... erythematosus #signs ... #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... #SLE #MSK #Musculoskeletal ... pathophysiology #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
of Lumbar Spine and ... Lupus - with Systemic ... (SLE), should have ... other symptoms ... Joint #Disorders #msk
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... Auto-Antibodies: - ANA ... #Systemic #Lupus ... autoantibodies #signs
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis ... Differential #Diagnosis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
: Pathogenesis and ... arthritis (RA) ... or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... : • Joint pain ... : • Symptoms limited ... #Systemic #Lupus
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