15 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... IgA nephropathy, lupus ... post-infectious GN ... #Differential #Diagnosis ... #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... GN • Active Urine ... (Dense deposit disease ... #MPGN #nephrology ... #diagnosis #renal
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
/nephritis • Lupus ... Post-infectious GN ... • Amyloid RPGN ... #nephrology #pathology ... comparison #table #diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... INTRINSINC RENAL Glomerulonephritides ... (GN) • Primary ... , Lupus Acute Tubular ... #nephrology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... pain (20%) Renal disease ... (30%): Glomerulonephritis ... signs #symptoms #diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... Erythematosus #SLE ... #CNS #neurology ... #rheumatology #
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
basement membrane; GN ... = glomerulonephritis ... atypical HUS; MPGN ... cluster, the diseases ... nephrotic #syndrome #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... vasculitis, and SLE ... #rheumatology #
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
, Busulfan • Disease ... Recurrence: Glomerulonephritis ... Goodpasture's syndrome, SLE ... #differential #diagnosis ... management #treatment #nephrology