10 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... #thrombocytopenic ... #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... Differential Diagnosis Table ... • Thrombotic Thrombocytopenic ... Primary #Thrombotic #Microangiopathy ... #TMA #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... : Thrombotic thrombocytopenic ... uremic syndrome (HUS ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Consumption: - Microangiopathy ... : DIC, TTP, HUS ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... almost) all TMAs cause ... triad of MAHA + thrombocytopenia ... #Thrombotic #Microangiopathy ... #TMAs #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Pregnancy - TTP/HUS ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN) RPGN has ... pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... diagnosis #algorithm #rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... Discontinuation of causal ... #sle #comparison ... #table #rheumatology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
urinalysis 3) microangiopathic ... . pauci-immune GN ... • Refractory cases ... overlap TTP or aHUS ... Renal #Crisis #rheumatology